Introduction Genetic disorders in children contribute to acute hospitalizations and mortality. Early diagnosis is critical for better outcomes but difficult to achieve due to atypical presentations for thousands of potential genetic diseases. Next-generation sequencing (NGS) is a precision

About the study Objective: This study aimed to quantify heterogeneity in the value for money of precision medicine (PM) by application types across contexts and conditions and to quantify sources of heterogeneity to areas of particular promises or concerns as the field of PM moves forward. Methods

In Thailand, the prevalence of chronic kidney disease (CKD) is 17.5% of the population (Ingsathit et al., 2010). According to Thailand’s National Health Security Office (2021), in each year, this public health agency spends approximately 10,000 million Baht in renal dialysis and 1,000 million Baht f

MEAs aim at early access to high-cost innovative medicines at pre-determined terms that can ensure the financial sustainability of healthcare systems. However, their successful adoption hinges on a consideration of various factors to address the unique challenges faced by different nations. The a

(Reuters) – Victims of thalidomide said on Saturday an apology from the German inventor of the drug that caused birth defects in thousands of babies around the world was too little too late.Thalidomide, developed by the German firm Gruenenthal, was marketed internationally to pregnant women in the l

Even in health care systems in which doctors do not bill for each test they administer, the use of diagnostic imaging like CT and PET scans has soared, as has patients’ radiation exposure, a new study has found.The study, published online on Tuesday in The Journal of the American Medical Association

For the first time, researchers have determined virtually the entire genome of a fetus using only a blood sample from the pregnant woman and a saliva specimen from the father.The accomplishment heralds an era in which parents might find it easier to know the complete DNA blueprint of a child months

CHICAGO — A drug that delivers a powerful poison to tumors without some of the side effects of traditional treatments can delay the worsening of breast cancer and also appears to substantially prolong lives, according to results of a study presented here Saturday.Besides representing an advance in t

CHICAGO — Taking periodic breaks from a commonly used treatment for prostate cancer could shorten men’s lives, researchers reported here on SaturdayIn a large study, intermittent hormonal therapy proved to be less effective than continuous therapy for certain men with metastatic prostate cancer.The

The more controversial of two papers describing how the lethal H5N1 bird flu could be made easier to spread was published Thursday, six months after a scientific advisory board suggested that the papers’ most potentially dangerous data be censored.The paper, by scientists at Erasmus Medical Center i