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Towards the introduction of pneumococcal conjugate vaccines in Bhutan: A cost-utility analysis to determine the optimal policy option

Abstract Background Due to competing health priorities and limited resources, many low-income countries, even those with a high disease burden, are not able to introduce pneumococcal conjugate vaccines. Objective To determine the cost-utility of 10- and 13-valent pneumococcal conjugate vacci

An economic analysis of chromosome testing in couples with children who have structural chromosome abnormalities.

Abstract BACKGROUND: Structural chromosome abnormalities can cause significant negative reproductive outcomes as they typically result in morbidity and mortality of newborns. The prevalence of structural chromosomal abnormalities in live births is at least 0.05%, of which many of them have paren

Economic costs of alcohol use in Sri Lanka

Abstract Aim Alcohol related disease conditions are responsible for a significant proportion of morbidity and mortality in Sri Lanka. This study quantified the economic cost of selected alcohol related disease conditions in Sri Lanka in 2015. Methods This study uses the prevalence-based cost

Economic Evaluation of Sildenafil for the Treatment of Pulmonary Arterial Hypertension in Indonesia

Abstract Background This study aims to assess the cost-effectiveness and budget impact of adopting sildenafil to the benefits package for the indication of pulmonary arterial hypertension (PAH), compared to beraprost. Methods Based on a societal perspective, a model-based economic evaluation

To include or not include: renal dialysis policy in the era of universal health coverage

SUMMARY POINTS •  End stage renal disease (ESRD) is a life-threatening condition that results in most patients requiring a lifetime of high cost renal dialysis •  Governments have grappled with the political, economic, and ethical challenges of providing treatment with their available budgets •

Prevention of non-communicable disease: best buys, wasted buys, and contestable buys

Increasing incidence of non-communicable diseases (NCDs) creates epidemiological and economic burdens everywhere and influences everyone regardless of sex and age.12 Four main NCDs (cardiovascular diseases, diabetes, cancer, and chronic respiratory disease) account for over 12 million premature deat

How can we make better health decisions: a Best Buy for all?

Abstract The World Health Organization (WHO) resolution calling on Member States to work towards achieving universal health coverage (UHC) requires them to prioritize health spending. Prioritizing is even more important as low- and middle-income countries transition from external aid. Countries w

Building Capacity for Evidence-Informed Priority Setting in the Indian Health System: An International Collaborative Experience

Abstract India’s rapid economic growth has been accompanied by slower improvements in population health. Given the need to reconcile the ambitious goal of achieving Universal Coverage with limited resources, a robust priority-setting mechanism is required to ensure that the right trade-offs arema

Economic evaluation of rotavirus vaccination in children of Bhutan

Abstract Background: Diarrhoea remains one of the top ten causes of under-five child morbidity in Bhutan, and rotavirus is a significant cause of child diarrhoeal hospitalisations. This study sought to determine the health outcomes, cost-effectiveness, and budget and human resource implications o

Growth and capacity for cost-effectiveness analysis in Africa

Abstract As economic evaluation becomes increasingly essential to support universal health coverage (UHC), we aim to understand the growth, characteristics, and quality of cost-effectiveness analyses (CEA) conducted for Africa and to assess institutional capacity and relationship patterns among a
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