Scientists have assembled a “timeline” of the unseen progress of Alzheimer’s before symptoms appear.A team at Washington University School of Medicine looked at families with a genetic risk of the disease.Writing in the New England Journal of Medicine, they say signs appeared up to 25 years before t

To learn how best to prescribe powerful drugs to children, Congress passed a law in the 1990s that rewarded drug makers for conducting clinical studies involving children. Among the incentives for cooperating companies was a possible six-month extension of protection from generic competition after a

Merck, the second-biggest U.S. drugmaker, on Wednesday said outside monitors recommended that its late-stage study of odanacatib, a new type of treatment, be stopped early because data has already shown it reduces fractures. Shares of Merck rose 4.2 percent on Thursday, on boosted hopes for the medi

(Reuters) – At an ill-fated press conference in 1984, U.S. Health and Human Services Secretary Margaret Heckler boldly predicted an effective AIDS vaccine would be available within just two years.But a string of failed attempts – punctuated by a 2007 trial in which a Merck vaccine appeared to make p

(Reuters) – GlaxoSmithKline is holding talks this weekend with Human Genome Sciences to agree a deal to acquire it for some $2.6 billion, after pursuing the U.S. biotech company for three months, sources familiar with the situation said on Sunday.The British pharmaceutical giant could sweeten its pr

WASHINGTON — A wide-ranging surveillance operation by the Food and Drug Administration against a group of its own scientists used an enemies list of sorts as it secretly captured thousands of e-mails that the disgruntled scientists sent privately to members of Congress, lawyers, labor officials, jou

Two days after Debra Demidon underwent in vitro fertilization, she gained more than 30 pounds in fluid and suddenly was struggling to breathe.Doctors diagnosed severe ovarian hyperstimulation syndrome (OHSS), a complication seen in some women who undergo fertility treatment. It landed Ms. Demidon in

PMAC 2016 Side Event (SE 026): Making decision makers accountable: better journalism – better chances of getting to Universal Health CoverageThis workshop will bring together journalists, bloggers and editors from around the world to share stories of reporting countries’ journey towards and efforts

PMAC 2016 Side Event (SE 014): Advanced Workshop in Methods for HTAThe methods of HTA have developed rapidly in the last decade. This is particularly the case in assessing the cost-effectiveness of interventions using modelling methods and in undertaking uncertainty analysis to guide decisions. Deci

All two to 17-year-olds in the UK are to be offered annual flu vaccinations.If 30% take up the offer, there will be 11,000 fewer hospitalisations and 2,000 fewer deaths each year, the chief medical officer for England says.The children will be immunised using a nasal spray rather than an injection,