Introduction Genetic disorders in children contribute to acute hospitalizations and mortality. Early diagnosis is critical for better outcomes but difficult to achieve due to atypical presentations for thousands of potential genetic diseases. Next-generation sequencing (NGS) is a precision

Abstract Return on investment (ROI) analysis is increasingly being used for evaluating the value for money of public health interventions. Given its potential role for informing health policies, it is important that there is a more comprehensive understanding of ROI analysis within the global

Indonesia issued the 2017 health technology assessment (HTA) guideline to facilitate researchers conducting economic evaluations based on standardised principles. However, our evaluation revealed no significant differences in adherence to its recommendation between HTA studies conducted before and a

There is a growing demand for public health insurance programmes to reimburse high-cost medicines, including those that do not represent good value-for-money. This demand is likely to inhibit financial sustainability, given the growth of new technologies and public demands for expanded access to car

Systemic sclerosis (SSc) patients often become refractory to proton pump inhibitors (PPI)—a standard treatment for gastroesophageal reflux disease (GERD)—and intolerant to PPI in combination with domperidone. PPI with alginic acid is an alternative treatment option, but alginic acid is costly. We

Abstract Background Typhoid vaccination has been shown to be an effective intervention to prevent enteric fever and is under consideration for inclusion in the national immunization program in Lao PDR. Methods A cost-utility analysis was performed using an age-structured static decision tree

Abstract Objective: The National Health Security Office in Thailand introduced a telemedicine program called “Telehealth/Telemedicine” in December 2020, which aimed to reimburse telemedicine services for patients with stable chronic diseases under the Universal Coverage Scheme (UCS). The current

Abstract Introduction: COVID-19 has accelerated the adoption of telemedicine for counseling, follow-up examination, and treatment purposes. The official guidelines in Thailand were launched to regulate or frame the protocols for healthcare professions and teams in different organizations. Obje

Highlights This report provides practical guidance for developing or updating health technology assessment (HTA) guidelines, especially in low- and middle-income countries where HTA is increasingly used as a priority setting tool for healthcare resource allocation and achieving universa

Highlights Economic evidence (cost-effectiveness information) can be used to inform policy-making process in supporting the movement towards universal health coverage. Published literature has focused on methods to set a cost-effectiveness threshold (CET) which can be used to guide the cost-eff