Target product profiles: opportunities and implications for health innovation development–a scoping review

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Highlights

By reviewing 120 Target Product Profiles (TPPs), this study identified key aspects of TPP development processes, stakeholder involvement, common themes, major limitations, and priorities for follow-up research.
Health technologies were classified into five categories, and the product attributes commonly considered were examined by technology type, revealing important variations across technologies.
Limitations of TPPs were identified and grouped into three categories: limitations in TPP design and application, limitations related to study design, and gaps in scientific evidence and knowledge.
Follow-up activities after TPP development are needed, including additional scientific research, implementation and feasibility studies, and regular updating of TPPs to maintain their relevance.