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This mission report summarises the activities and discussions during the second meeting of the Unit for Health Evidence and Policy (UHEP), held on September 1st, 2022. This meeting aimed to promote the understanding of Health Technology Assessment (HTA) topic prioritisation in Lao PDR and sharing Thailand’s experience of topic prioritisation processes for HTA. The meeting was organised by the Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit (LOMWRU), University of Health Sciences (UHS), and the Ministry of Health (MoH), Lao PDR. Logistics of the meeting was supported by Tadam Solathtanavong and LOMWRU team. The meeting was opened by the Minister of Health for Laos: His Excellency Dr Bounfeng Phoummalaysith. Representatives from the Health Intervention and Technology Assessment Program (HITAP), the Ministry of Public Health (MoPH), Thailand, led by Assoc. Prof. Wanrudee Isaranuwatchai and Dr. Yot Teerawattananon, contributed to the content and exercise delivered during the meeting. Facilitators for the exercise included Chittawan Poonsiri, Chotika Suwanpanich, Kumaree Pachanee, Manilung Nalongsack, Manta Korakot, Papada Ranron, Praewa Kulatnam, Thamonwan Dulsamphan, and Waranya Rattanavipapong. The report was prepared by Manit Sittimart with inputs from Saudamini Dabak, Assoc. Prof. Wanrudee Isaranuwatchai, Dr. Yot Teerawattananon, Prof. Mayfong Mayxay, Prof. Elizabeth Ashley, and Dr. Sysavanh Phommachanh. The statistical analysis of participant feedback was conducted by Chulathip Boonma.