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Indonesia issued the 2017 health technology assessment (HTA) guideline to facilitate researchers conducting economic evaluations based on standardised principles. However, our evaluation revealed no significant differences in adherence to its recommendation between HTA studies conducted before and after the guideline was disseminated (except for outcome choice), and most recommendations were not adopted. We reflected that the guideline was hard to follow, inconsistent, and offered limited justification. Thus, we suggested improving the 2017 HTA guideline, at least in these areas. On December 2022, in response to the rapid development of health technology, the revised guideline was issued with the support of multiple international development agencies.

Here we highlight key items of the revised guideline, outline the potential impact on Indonesia’s HTA landscape, and propose suggestions for Indonesia and other countries developing HTA guidelines.

Open access: https://www.sciencedirect.com/science/article/pii/S2772368223001403