ต้นทุนอรรถประโยชน์ของการตรวจคัดกรองมะเร็งเต้านมด้วยเครื่องเเมมโมแกรม 1 ครั้งในชีวิตของผู้หญิงไทย (2556)

Abstract Cost-utility of once-in-a-lifetime breast cancer screening with mammography in Thai women

Thunyarat Anothaisintawee*,†, Narisa Tantai‡ and Yot Teerawattananon*

*Health Intervention and Technology Assessment Program (HITAP), Ministry of Public Health

†Department of Family Medicine, Faculty of Medicine, Ramathibodi Hospital

‡Pharmaceutical Department, Faculty of Medicine Siriraj Hospital, Mahidol University

Breast cancer is the most common cancer in Thai women with the age-standardized incidence rate of

25.6/100,000. Among mammography, clinical breast examination, and self breast examination, only mammographic

screening showed efficacy in decreasing mortality rate from breast cancer. But an organized

mammographic screening has not been established in Thailand due to lack of human resource and infrastructure.

The study aimed to evaluate the cost-utility of establishing a once-in-a-lifetime breast cancer

screening with mammography in Thai women aged 40-49 years and aged 50-59 years through decision

tress. Societal perspective was used to estimate both direct and indirect costs. Incremental cost-effectiveness

ratios (ICER) were calculated and sensitivity analysis was performed by applying probabilistic sensitivity

analysis. ICERs of establishing a once-in-a-lifetime breast cancer screening with mammography in

Thai women aged 40-49 years and 50-59 years were 1,847,481 Bath/QALY and 1,368,764 Bath/QALY,

respectively. The measure was not found to be cost-effective in Thailand